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ERR biology, coactivation, and the exercise-mimetic concept ERRs operate as transcription factors that bind response elements in promoters and enhancers of metabolic genes, recruiting coactivators such as PGC-1/ and chromatin-remodeling complexes

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We found that phosphorylation of the S114 priming residue altered the nucleocytoplasmic distribution of NHR-49 and was necessary for subsequent phosphorylation of adjacent residues by recombinant KIN-19 (Figs

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